Effects of aspirin and garlic on cyclooxygenase-induced chemiluminescence in human term placenta.
نویسندگان
چکیده
The spontaneous emission of chemiluminescence appears to reflect changes in the intracellular steady-state concentration of oxygen radicals. Stimulation of arachidonic acid metabolism in human platelets also induces chemiluminescence, which indicates the formation of highly reactive species by cyclooxygenase andlor lipooxygenase [1,2]. It was observed that arachidonic acid, linoleic acid and linolenic acid can induce luminol-induced chemiluminescence in human term placental villi. The luminol-dependent chemiluminescence activity after addition of these fatty acids was investigated after incubation of villi with aspirin and garlic extract.
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 25 1 شماره
صفحات -
تاریخ انتشار 1997